Modeling Podocyte Ontogeny and Podocytopathies with the Zebrafish

Modeling Podocyte Ontogeny and Podocytopathies with the Zebrafish

Blog Article

Podocytes are exquisitely fashioned kidney cells that serve an essential role in the process of blood filtration.Congenital malformation or damage to podocytes has dire consequences and initiates a cascade of pathological changes leading BROWN RICE CAKES UNSALTED to renal disease states known as podocytopathies.In addition, animal models have been integral to discovering the molecular pathways that direct the development of podocytes.In this review, we explore how researchers have Pentair Automatic Feeder Parts used the zebrafish to illuminate new insights about the processes of podocyte ontogeny, model podocytopathies, and create opportunities to discover future therapies.